Gene expression profiling by microarrays – clinical implications
نویسندگان
چکیده
منابع مشابه
Gene expression profiling of alveolar rhabdomyosarcoma with cDNA microarrays.
Several forms of human sarcoma, lymphoma, and leukemia are characterized by somatically acquired chromosome translocations that result in fusion genes that encode chimeric transcription factors with oncogenic properties. We have used cDNA microarrays containing 1238 cDNAs to investigate the gene expression profile of a group of seven alveolar rhabdomyosarcoma (ARMS) cell lines characterized by ...
متن کاملProfiling C. elegans gene expression with DNA microarrays.
Copyright: © 2006 Douglas S. Portman. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. To whom correspondence should be addressed. E-mail: [email protected] Profiling C. elegans gene expression with...
متن کاملAnalysis of gene expression by microarrays
During the five years or so since their introduction for use in gene expression monitoring, DNA microarrays have come a long way. From a few dozen cDNAs spotted on glass or nylon membranes to the completion of the ‘full genome chip’ for S. cerevisiae, we have reached a point at which genome-wide monitoring of expression levels of all human and mouse genes seems close at hand. With a working dra...
متن کاملOptimal gene expression analysis by microarrays.
DNA microarrays make possible the rapid and comprehensive assessment of the transcriptional activity of a cell, and as such have proven valuable in assessing the molecular contributors to biological processes and in the classification of human cancers. The major challenge in using this technology is the analysis of its massive data output, which requires computational means for interpretation a...
متن کاملGenetic expression profiling of parotid neoplasms by cDNA microarrays.
Differentially expressed genes in various benign and malignant salivary gland tumours were identified by use of cDNA microarrays containing 19,000 human expressed sequence tags. Samples were derived from 5 patients with pleomorphic adenoma, 4 with Warthin's tumour, one with clear cell carcinoma, and 2 with mucoepidermoid carcinoma. Tumours were classified by using a subset of 486 genes. Benign ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 2007
ISSN: 0007-0920,1532-1827
DOI: 10.1038/sj.bjc.6603486